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Lysine-specific modifications of p53: a matter of life and death

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We expressed EccA 3 -GFP in a M

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Katsuyama, T

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IDO inhibits the function of immune cells through a specific L-Trp depletion pathway, where L-Trp depletion by IDO leads to its dissociation with L-Trp tRNA, thus activating general control non-derepressible 2 (GCN2) due to the presence of its allosteric regulatory site which senses free tRNAs (47, 48)

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In skeletal muscle, AKT phosphorylation activates mTORC1, increasing ribosomal protein S6 kinase activity and protein translational efficiency the primary molecular mechanism underlying the hypertrophic stimulus

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