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Abd-Rabou AA, Zoheir KMA, Kishta MS, Shalby AB, Ezzo MI

10.7554/eLife.27055 Elife 45 CrtesN.LiraA.SilvaJ.CarvalhoE.Prates-SyedW.HamaguchiB.et al

Biophys., 149, 102 (1972)

Excessive Fe 2+ is oxidized to Fe 3+ by ferroportin (FPN) to maintain intracellular iron homeostasis (Gao et al., 2015), while heme oxygenase-1 (HO-1) supplementation accelerates erastin-induced ferroptosis (Kwon et al., 2015)