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I get flustered and lose my train of thought a couple of times

Ans: Side effects are infrequent when given properly by a trained clinician

and track standardized outcomes (pain, function, mobility, gut symptoms) over time

On the other hand, Cu(I) binds in a linear geometry involving two of the three histidine residues (His6/13/14) in a dynamic exchange 12

Including clinically diagnosed cases alongside genetically confirmed patients enhances the real-world representativeness of this review but introduces diagnostic heterogeneity and potential misclassification, which may limit the generalizability of treatment-related conclusions, particularly regarding the efficacy of oral vitamin B12 therapy