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ultrasound) anti-inflammatory advice joint mobilization ice or heat treatment exercises to improve flexibility and strength education activity modification advice a gradual return to activity program Other intervention for a sprained thumb Despite appropriate physiotherapy management, a small percentage of patients with a thumb sprain do not improve adequately and may require other intervention

These affect how well a particular drug is distributed around a persons body (called the volume of distribution), or how fast a person excretes that drug (called the drug clearance)