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A pharmaceutical composition comprising: about 0.25 % to about 10 % of a reducing agent-choline ester, optionally, about 0.05 % to about 1.0 % of a biochemical energy source, about 0.25 % to about 1 % buffer, about 0.2 % to about 0.6 % tonicity agent, and about 0.1 % to about 0.4 % viscosity agent

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Lastly, epidemiological data suggests G6PD-d may modify several cardiovascular risk factors that can contribute to the development of ASCVD

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Taken together, these results suggest that 1- pravastatin induces liver mitochondrial redox imbalance that may explain the hepatic side effects reported in a small number of patients, and 2- the co-treatment with safe antioxidants neutralize these side effects