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Simultaneous injection of glucose and insulin can transiently overcome deficit, administration of exogenous BHB can overcome the deficit by bypassing and going straight through alpha-hydroxybutyrate into the Krebs cycle

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Materials and methods Experimental methods Fasting blood samples were collected from fifty non-diabetic subjects and fifty-four diabetic patients at baseline and at follow-up visits after 4 and 8 weeks of anti-diabetic treatment, as described previously in Acharya et al

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This signal and metric changes from the 4w group to the 6w group may occur because in the demyelination process, edema has a stronger effect on the change in T 2 WI signal and T 2 -nor value, resulting in abnormal hyperintensity 22,23