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With a proven safety profile established through phase II clinical trials in Parkinsons and liver disease [260, 261], MitoQ supplementation effectively rejuvenates vascular EC function in aged mice by restoring mitochondrial superoxide balance and enhancing NO bioavailability [262], a finding that was subsequently validated in a rigorous randomized, placebo-controlled, double-blind clinical trial involving healthy older adults [263]

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doi: 10.3233/JAD-142391

CyTOF data were normalized using bead-based time normalization according to manufacturers instructions, then cleaned using the Gaussian parameter discrimination method (Supplementary Fig

Because of the limited research into this treatment option, it is considered a more alternative, but perfectly safe, way to manage the symptoms of fluid retention