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However, during apoptosis, the mitochondrial membrane potential is lost and the mitochondrial permeability transition pore (MPTP) remains open, allowing TMRE to escape into the cytoplasm, resulting in a significant reduction of orange-red fluorescence within the mitochondria [44]

Growing up in Farmington, Utah, alongside fellow co-founder Nathan (Nate) Hill, the two developed a close friendship that would later inspire their collaboration

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209, 721 (2015), Abstract Autocrine VEGF maintains endothelial survival through regulation of metabolism and autophagy: C.K