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Funding This research was supported by the National Nature Science Foundation of China (Nos

Lin et al., 2005

Research Summary The foundational research on GHK-Cu traces back to Pickarts 1973 discovery that a low-molecular-weight factor in young human plasma could stimulate aged liver tissue to synthesise proteins at rates comparable to younger tissue

This is why medical weight loss treatments have gained significant attention in recent years

KLFs, particularly KLF2 and KLF4, are critical shear-responsive transcription factors that maintain the vascular barrier and endothelial quiescence by promoting anti-inflammatory and anti-thrombotic phenotypes and regulating metabolism [200, 201]