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Description

Schrmann, P

E.CaronG

These results demonstrate the translational potential of MAT2A inhibition and support its broader applicability across multiple malignancies

Animals injected with PKH26-labeled t-butyl hydroperoxide (t-BHP) treated RBCs, to induce oxidative stress, demonstrated an increase in the number of stalled or unmoving RBCs and reduced blood flow velocity in the cerebral vasculature within 14 h and 24-h after RBC injection, as compared to control animals injected with phosphate-buffered saline (PBS) (Zhang et al., 2023)