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The most important aspect of our study is in the novel evidence showing that prophylactic T4 treatment may contribute to remyelination, since this treatment was able to promote an increase of new OLs generated from OPC proliferation and differentiation (Zhang et al., 2009)

Transcriptional regulation of ROS homeostasis by the ERR subfamily of nuclear receptors

Consequently, unwanted replacement of Cys with Se-Cys might interfere substantially with efficient electron transfer within the electron transport chains operating in photosynthesis and respiration (Van Hoewyk, 2013) The thiol group of Cys is critical for coordinating Fe/S clusters in numerous electron transfer reaction centers of proteins (Roland et al., 2020)

Drainage and floodwaters from shale-rich mountainous regions contribute to Se-enriched lowland reservoirs and floodplains, e.g., in Californian water systems [17,18,19]

Some areas may have shallow waters that could limit boat access or hinder activities such as swimming