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If they cannot be fully addressed, this inflammatory immune response will continue

Nature 498(7453):E4-6

[PubMed: 9887164] 4

& Zierath, J

Though histone methylation is not globally reduced in the liver, it is still altered in such a way that reinforces the transcription-promoting effects of DNA hypomethylation: Repressive marks are decreased, and activating marks are increased