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Results from the phase 1 trial and open-label extension evaluating BIIB078 in adults with C9orf72 -ALS

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These were mass spectrometry connected with gas chromatography (GCMS), matrix-assisted laser desorption with ionization time-of-flight (MALDI-TOF/TOF), and mass spectrometry connected with liquid chromatography (HPLCMS/MS)

NMN plays a pivotal role in several important biological processes, including energy metabolism, cellular aging, circadian rhythm regulation, DNA repair, chromatin remodeling, immunity, and inflammation