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Risk score thresholds that provided sensitivity 80% (NFS -5.69, Hung 9, Sinn 9, BARD 2, and ALBI -3.07) had poor specificity (0%, 22%, 32%, 28%, and 22%, respectively) and PPVs were 6cm (n=26), tumor number7 (n=37), vascular invasion (VI) (n=23) and extrahepatic spread (EHS) (n=37)

PMID: 12887507 [Para 252] Nucci C, Palamara AT, Ciriolo MR, Nencioni L, Savini P, D'Agostini C, Rotilio G, Cerulli L, Garaci E

doi: 10.22376/ijpbs.2018.9.1.b198-203 55 KhodjaY

These models differ in their seed cells, scaffolding materials, structural complexity, culture methods, and aging induction strategies (Table 2)

However, an elevation of B12 in ones serum can be tied to the MTHFR gene variation , as those with the MTHFR gene variation may be unable to properly use non-methylated B12