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Altschul et al

If you experience unexpected symptoms whilst taking B12, discuss with your GP whether continued supplementation is necessary or whether dose adjustment might help

In one study, it affected Egr , Nos , Srf , Vegfr , Akt1 , Plc, and Kras gene expression in the vessel that provides an alternative operating pathway (i.e., the left ovarian vein as the key for infrarenal occlusion-induced inferior vena cava syndrome in rats) (Vukojevic et al., 2018)

Importantly, there was an apparent improvement in cardiac function in the cAtg3-KO mice following treatment [8]