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The exact mechanism by which vitamin D improves lipid markers is still under debate 6

Acta Neuropsychiatr

Reprod Biol Endocrinol (2013) 11(1):115

It has not yet been definitively shown whether the [NAD + ] or the [NAD + ]/[NADH] regulates mostly nuclear-localized SIRT7, but the very low nucleocytoplasmic [NADH] in mammalian cells suggests SIRT7 is likely regulated by [NAD + ]