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Moreover, IGF-1 stimulates androgen receptor signaling by increasing adrenal and gonadal androgen synthesis as well as androgen receptor transactivation by nuclear extrusion of the androgen receptor cosuppressor FoxO1 [17, 18]

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Based on in silico analysis, GPXs were predicted in chloroplast, mitochondria, cytosol, and ER localizations (Rouhier and Jacquot, 2005), and demonstrated high level of sequence similarity with strictly conserved cysteines and motifs (Dietz, 2011)

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