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Since inflammation of the large intestine affects brain function through braingut interaction, patients with colitis are at a high risk of developing psychiatric disorders, such as depression and anxiety, during the exacerbation period 43,44

10.1016/j.brainres.2023.148715 145 ShenJ

Further observations suggested that gustducin may be one, but not the only player in sweet taste transduction, since: (1) only a subset of sweet taste receptor expressing cells are positive for gustducin, with publications reporting from 1/10 to 2/3 of double positive cells (Hoon et al., 1999