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RNA-binding elements Although charge-reversal mutations within RBE2 and RBE3 did not individually impact rescue of miR-7 degradation in ZSWIM8-deficient cells, combined mutation of all three RBEs exacerbated the defect caused by mutating RBE1, leading to severe loss of both TDMD in cells and polyubiquitylation in vitro (Fig

Additionally, these GSTs are also largely distributed among kingdoms since they are found in mammals, nematodes, insects, and trypanosomatids but not fungi (Table 2)

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Gynecomastia is a benign enlargement of the male breast resulting from a growth of the glandular tissue of the breast