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Although MTHFR does not directly cause B12 deficiency, research suggests that people with the MTFHR C677T mutation have a significantly higher risk of deficiency

Tick-Borne Meat Allergy: Many Carry Alpha-Gal Antibodies Without Symptoms More Health News Medically Reviewed on 6/23/2026 Mayo Clinic: "Vitamin B-12." National Institutes of Health: "Vitamin B12." Oregon State University: "Vitamin B12." Top What Happens if You Take Too Much Vitamin B12 Related Articles 22 Healthy Foods High in B VitaminsAny deficiency of B vitamins can lead to various health conditions

Do not use AOD-9604 or 5-Amino-1MQ if you have active thyroid disease, uncontrolled cardiovascular conditions, or are pregnant or breastfeedingsafety data in these populations is absent