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MOTS-C does not bind a classical cell-surface receptor

Strict compliance supports safer outcomes across diverse healthcare settings

and, the whole charge-the-whistleblower thing

However, normoxic elevation and activation of HIF can be caused either by loss/inactivating mutations in VHL (occurring in most clear cell renal cell carcinomas) or by oncogenic pathways that increase the transcription, translation, and/or activity of the HIF- subunit in non-RCC tumors [6]