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RAGE pathway activation is associated with cell injury and dysfunction, in diverse renal cell types, including glomerular cells (podocytes and mesangial cells), tubular epithelial cells, and endothelial cells

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Loss of the exocyst complex component EXOC3 promotes hemostasis and accelerates arterial thrombosis

Studies were performed independently, with patient selection, surgical parameters, selection of BPCDX size and thickness, post-operative medications, clinical data collection and measurement of outcome parameters dictated by the local investigators, preventing a combined analysis of outcomes