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For instance, in preclinical models, long-term ketamine exposure increases the expression of GABA receptor subunits in the prefrontal cortex while simultaneously reducing glutamate receptor subunits, impairing synaptic signaling and cognitive function ( Ketamine also downregulates brain-derived neurotrophic factor, particularly in the hippocampus, exacerbating deficits in synaptic plasticity and cognitive functions

doi: 10.1186/s12941-021-00438-7 331

therefore, the appearance of this protein in the serum of AIS patients is thought to be indicative of increased BBBP (186)

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In stock Contents: 10 mg lyophilized (freeze-dried) powder provided in a 3 ml vial, sealed and sterile