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Common IF patterns include Every-other-day fasting (EODF), whole-day fasting (1 or 2 days of fasting per week), time-restricted feeding (TRF, where energy intake is typically limited to an 812 h window), and periodic fasting (PF, fasting for 2 days following 5 days of unrestricted eating) (29) (Figure 1)

The full search strategy on different databases is provided in Appendix 1

Similarly, glycosylation and polarity influence solubility and release, as glycosylated polyphenols, being more polar and hydrophilic, are more readily released from the food matrix and therefore more bioaccessible in the gastrointestinal tract (Zhu et al., 2020a, b)

Zhong WR, Huang YX, Cui JP

Priced at $2.2 million, financial access is another challenge for Casgevy