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For patients who have difficulty absorbing B12 through the digestive tractsuch as those with pernicious anemia, gastrointestinal disorders (like Crohns disease or celiac disease), a history of gastric bypass surgery, or those with severe B12 deficiencyour providers often recommend intramuscular B12 injections

When you inhibit NNMT, your cells can make more NAD+, a molecule that powers your mitochondrial energy factories

Your body usually eliminates the excess vitamin through excretion in the urine by the kidney

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When symptoms are present, they are almost always caused by the underlying condition driving the elevation , not by the B12 itself