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What they found: Darkening of existing nevi in 85 % of patients New nevi in 30 % Atypical features on dermatoscopy in 40 % Two cases of malignant melanoma in the followed cohort No evidence of a causal relationship, but associative correlation Why it matters: These are the most serious published safety data for Melanotan II

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Accepted: Published: Version of record: Issue date: DOI:

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I.ZhangW

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10.1016/j.plipres.2009.08.004 14

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Fukui K, Ushiki K, Takatsu H, Koike T, Urano S: Tocotrienols prevent hydrogen peroxide-induced axon and dendrite degeneration in cerebellar granule cells

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