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318 In addition, overactivation of GABAergic signaling may further worsen striatal function by inhibiting dopamine release

Fer-1 (Glpbio, GC10380) was initially dissolved in dimethyl sulfoxide (Sigma, D2438) and diluted with 0.9% NaCl solution (Beyotime, ST341) to achieve a final concentration of 0.25 mg/mL Fer-1 and 0.1% DMSO

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Two-dimensional (2D) polyacrylamide gel electrophoresis (PAGE) showed that SLC7A11, OTUB1, and SLC3A2 were detected in association with the ~150-kDa complex (Fig