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17,228,235 These modifications considerably increase nuclease tolerance and prolong the half-life of nucleic acids while effectively avoiding the inflammatory reactions triggered by PS modification, demonstrating a higher safety and activity

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Of interest to the topic to be discussed in this review, studies highlighting cell-type specific epigenetic changes [91], including in OLGs, started to emerge in the field of neurodegeneration

For a long time, the primary method of administration was subcutaneous injection, which is fantastic for localized issuesa specific tendon, a nagging joint, or a direct muscle injury

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