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Considerations for Patients with Malabsorption Disorders Those with malabsorption issues, like celiac disease or Crohns disease, might need more B12

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The standard dosage for severe deficiency typically starts with 1 mg daily injections, transitioning to weekly and then monthly maintenance doses

This process requires adequate B vitamins including B12 for proper function

When levels remain persistently elevated particularly without supplement use further assessment may be recommended to look for an underlying cause