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For consistency across studies, document solvent, concentration, storage temperature, freezethaw cycles, and light exposure conditions in experimental records

Following OA induction, the rabbits were randomly divided into four groups with 8 subjects, each receiving a different weekly intra-articular treatment starting four weeks after the first collagenase injection

As described by Cant et al

Those with pre-existing conditions such as irritable bowel syndrome (IBS), functional dyspepsia, or gastritis may be more prone to experiencing stomach upset from supplements generally, including B12 preparations

This keeps B12 levels just right