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Other acivicin-regulated genes are similarly affected by toxic metals (Cd 2+ and Hg 2+ ) (Fig

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The glutathione redox state of the matrix is maintained separately from the IMS and the cytosol Our results also imply that the IMM prevents the equilibration of the glutathione pools in matrix and IMS in vivo and in vitro , and that the matrix has to rely on its own glutathione reduction machinery for maintaining E GSH

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