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91 In addition, lactylation at K91 of TFEB inhibits its interaction with the E3 ubiquitin ligase WWP2, leading to reduced ubiquitination and proteasomal degradation of TFEB, thereby resulting in enhanced TFEB activity

NascimbeniFPaisRBellentaniSDayCPRatziuVLoriaPet al

Although the high caloric content of fats may be bad news for the dieter, it says something about the efficiency of natures designs

74 Therefore, it is necessary to view the risk estimates generated by the PREVENT calculator as an informative tool in shaping discussions about whether specific therapies are appropriate, and the PREVENT risk estimates should not be used in isolation to make intervention decisions

[DOI] [PubMed] [Google Scholar] Turesky RJ, Le Marchand L