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Less common symptoms include headaches, a thumping heart (palpitations), altered taste, loss of appetite, pale appearance, sore mouth or tongue and ringing in the ears (tinnitus)

Variations in genes associated with inflammation, oxidative stress response, and neuronal function have been linked to increased susceptibility to neuropathy in diabetes patients

Do not administer this drug to the following patients: 1) Patients with hypersensitivity to the components of this drug 2) Patients with hypercalcemia, hypercalciuria 3) Patients with calcium oxalate stones 4) Patients with renal impair 5) Patients who are immobilized in a hospital bed 6) Sarcoidosis 7) Patients with pseudoparathyroidism 3

Long-term follow-up of the second and third studies found that the injectable treatments (both monthly or every two months) remained effective after three years

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