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Endocr Metab Immune Disord Drug Targets [Internet]

Curcumin has been shown to re-polarize these M2-like macrophages towards an M1-like phenotype, which is associated with anti-tumor activity and pro-inflammatory cytokine production

Integrated preclinical to first-in-human to indication-specific randomized clinical trials (RCTs) would be ideal candidates to combine mechanistic readouts (local drug/metabolite concentration, biofilm imaging, single-cell viability) with clinical readouts and, in advanced preclinical studies, local drug/metabolite concentrations

Helminth therapy is a promising alternative therapeutic for IBD that has gained some attention in the last two decades

It brightens the complexion, reduces the appearance of dark spots and fine lines, and restores the skin's youthful radiance