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In those human studies, the results were mixed, with some showing that oxidative damage was reduced with long term supplementation [15, 21] and another showing no reduction in oxidative damage [16]

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In contrast, the CAT and GSH contents were significantly increased by 20% and 21%, respectively, in CCM+GEN- than GEN-treated group and by 45% and 60%, respectively, in CCM+NaS- than NaS-treated group

Pharmacological effects of Chatuphalatika in hyperuricemia of gout

When p62 is knocked down via RNA interference, the expression of NQO1, HO-1 and ferritin heavy chain is decreased, exacerbating erastin-induced ferroptosis (45,46)