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The induction of ferroptosis involves specific pathways: redox-active iron, iron-dependent peroxidation enzymes

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Two groups mice received an intraperitoneal injection of GSH or Fer-1 weekly for 12 weeks, and one group mice received with normal saline

These biologics have become the standard treatment for moderate to severe IBD patients, as well as for those who are refractory to conventional therapies, steroid-dependent, or steroid-resistant