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Drug-metabolizing cytochrome P450s in the brain

All previously discussed protective agents are summarized in Table 1, which serves as a comparative table to illustrate the molecular target, experimental model, and key outcomes associated with each protective agent

Relamorelin was responsible for glycemic control worsening in 14.5% of patients in a dose-dependent manner

184,185 Upregulated USP20 expression in oxaliplatin-resistant HCC cells is associated with poor prognosis, while genetic knockdown or pharmacological inhibition of USP20 can trigger ferroptosis and increase the sensitivity of HCC cells to oxaliplatin both in vitro and in vivo

The overview below is educational only not medical advice