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Similarly, mouse immature DCs were genetically engineered to secrete exosomes expressing the Lamp2 protein fused with the iRGD peptide (CRGDR/KGPDC) and demonstrated highly efficient targeted drug delivery to v integrin-positive breast cancer cells, consequently inhibiting tumor growth 36

Adikari, S

In endothelial cell models, BPC-157 significantly enhanced ERK1/2 phosphorylation in a dose-dependent manner, leading to increased cellular proliferation, migration, and vascular tube formation mediated through downstream activation of transcription factors c-Fos, c-Jun, and EGR-1

This occurred as it had been noted in BuddChiari syndrome BPC 157 therapy, with either intraperitoneal or per-oral application [27], indicative for the syndrome of the occluded superior sagittal sinus