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Common Causes of "Leaky Gut" Multiple factors can contribute to increased intestinal permeability, and while scientific research continues to explore the full extent of these connections, the following are commonly recognized triggers: Diet especially when its high in processed foods, refined sugars, and artificial additives and preservatives, can disrupt gut microbiota and weaken the intestinal barrier

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J Agric Food Chem 62:77217729 Kim J-S, Kwon Y-S, Sa Y-J, Kim M-J (2011) Isolation and Identification of Sea Buckthorn ( Hippophae rhamnoides ) Phenolics with Antioxidant Activity and -Glucosidase Inhibitory Effect