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Gut microbe-derived metabolite trimethylamine N-oxide accelerates fibroblast-myofibroblast differentiation and induces cardiac fibrosis

This was the transition period to agricultural societies and since then fermenting food has become an important part of our diet

The qPCR results showed that the mRNA expression levels of CYP51 (20.86 0.55) and SQLE (21.85 0.32) in the 5 mg/kg/d group were significantly higher than those in the control group (19.94 0.70, 20.63 0.51) ( p 0.05) (Figure 9)

Protein sequence and structure analysis of three unidentified genes To further explore the evolutionary relationship between unidentified DEGs and identified DEGs

Nutr Metab (Lond) 8:34 James SJ, Melnyk S, Jernigan S, Cleves MA, Halsted CH, Wong DH, Cutler P, Bock K, Boris M, Bradstreet JJ, Baker SM, Gaylor DW (2006) Metabolic endophenotype and related genotypes are associated with oxidative stress in children with autism