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This approach is justified by the study of Vickery and Hamlin(101), who found, on both clinical and pathologic grounds, that the disease may remain static and the clinical condition unchanged over many years

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If you notice persistent nail abnormalities lasting more than 46 weeks, particularly when accompanied by other symptoms such as fatigue, pallor, shortness of breath, pins and needles, or cognitive changes, you should consult your GP for proper assessment