pdb glutathione s transferase RCSB RCSB PDB - 2C3N: Human

The goal is controlled redox balance, not zero oxidants

Askari, B

Targeting glutamine metabolism transporter inhibitors Gln metabolism has received increasing attention in the process of material transport and energy metabolism in cancer cells, and increased Gln catabolism in cancer cells has been associated with increased expression of Gln transporter proteins

Bronzato, Vanessa Gallego Arias Pecorari, Jennifer Santos Pereira, Talita Tartari, Adriana de Jesus Soares, Brenda P

In some embodiments, pharmaceutical formulations of the present disclosure may include, lipid nanoparticle that contain disulfiram formulated with D--tocopheryl polyethylene glycol 1000 succinate (vitamin E-TPGS-modified) as described in Baneerjee et al.2019 (Banerjee P, Geng T, Mahanty A, Li T, Zong L, Wang B