glutathione-specific gamma-glutamylcyclotransferase 1

glutathione-specific gamma-glutamylcyclotransferase 1 Metabolic orchestration driven by GGCT: diverting glutamine to glutathione biosynthesis while enhancing glucose anaplerosis for tumor proliferation γ-Glutamyl Cycle

Name: glutathione-specific gamma-glutamylcyclotransferase 1 Metabolic orchestration driven by GGCT: diverting glutamine to glutathione biosynthesis while enhancing glucose anaplerosis for tumor proliferation γ-Glutamyl Cycle
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Glutamyl Cycle Gamma Glutamyl Transpeptidase: Redox Regulation and Drug Resistance PMC International Journal of Oncology RCSB PDB 6K95: Crystal structural of human glutathione specific gamma glutamylcyclotransferase 2 (ChaC2) Enhanced glutathione levels confer resistance to apoptotic and ferroptotic programmed cell death in NEIL DNA glycosylase deficient HAP1 cells ScienceDirect

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10.1016/S0891-0618(97)00051-3 128 MajdS.PowerJ

For the anti-inflammatory therapies, the anti-macrophage-derived high mobility group box 1 (HMGB1) neutralizing antibodies therapy decreased the neuropathy of OIPN by neuroinflammation modulation in an OIPN mice model [161]