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A general finding is that obese patients fulfilling criteria for MetS together with low IGF-1 plasma levels tend to develop a worse cardiovascular disease outcome than those with mid-normal to high-normal IGF-1 levels [213]

J Clin Endocrinol Metab (2001) 86(8):384552.10.1210/jcem.86.8.7731 203 GoodyerCGZogopoulosGSchwartzbauerGZhengHHendyGNMenonRK

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