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Clinical, 40 , 103503

47 HeL.KimT.LongQ.LiuJ.WangP.ZhouY.et al (2012)

Other side effects include gastrointestinal problems, insomnia and headaches

Akt also inhibits apoptosis by deactivating pro-apoptotic protein Bcl-2 antagonist of cell death (BAD), as well as by promoting the breakdown of p53 as a pro-apoptotic protein via activation of E3 ubiquitin-protein ligase MDM2 [79]