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Resistance in c-Met Inhibitors and Sorafenib and Combined Inhibition of HGF/c-Met and Other Pathways C-Met inhibitor therapy has failed to result in satisfactory outcomes in phase III clinical trials for HCC

By seemingly targeting the growth hormone axis through their supposed distinct mechanisms of action, Tesamorelin and Ipamorelin may collectively stimulate the pituitary gland, thereby potentially enhancing the release of endogenous growth hormone

R.Ramrez Y AyalaR.Ochoa-VelascoC.BrambilaE.Avila-SosaR.Prez-FernndezS.et al (2017)

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