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Pernicious Anemia: This is an autoimmune disorder where the body mistakenly attacks a protein in the stomach called "intrinsic factor." Without this protein, you simply cannot absorb B12 from food, making injections a lifelong necessity

(PubMed) Essen A, Santaolalla A, Garmo H, et al

Its ability to activate sirtuins, enhance DNA repair, regulate metabolism, influence fat cell metabolism in preclinical models and support mitochondrial health positions it as a compelling candidate for further investigation

Yes, its mechanism of inhibiting NNMT can contribute to increased fat metabolism and decreased fat storage, supporting weight loss efforts