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Upregulation of the mitochondrial calcium uniporter (MCU) contributes to calpain/OPA-1-mediated inhibition of mitophagy, suppressing excessive apoptosis through OPA1 [99]

[DOI] [PubMed] [Google Scholar] 90.Ochiai R., Chikama A., Kataoka K., Tokimitsu I., Maekawa Y., Ohishi M., Rakugi H

You can also develop spinal stenosis at a younger age if youre born with a narrow spinal canal or if you experience a spinal injury

However, our monoparatopic and biparatopic VNARs demonstrated equal or increased affinity and potency (in vitro) when compared to clinically approved anti-TNF- biologics