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MASLD serves as an umbrella term that encompasses a broad spectrum of pathological liver changes from simple hepatic steatosis to steatohepatitis associated with metabolic dysfunction, which can lead to fibrosis and eventually progress to cirrhosis or hepatocellular carcinoma (HCC), while simultaneously increasing the risk of cardiovascular diseases (CVDs) and extrahepatic malignancies [1]

Chem Rev 1999;99:2683710

10.1016/j.rmed.2004.02.007 153 LiD.CongZ.YangC.ZhuX

Theoretically, lactate can function as an energy substrate during the ischemic phase, shuttling from astrocytes to neurons to provide energy and protect neuronal cells from ischemic damage

16, 272282, doi: 10.1016/0045-2068(88)90015-6 (1988)