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Anti-MuSK antibodies are of the IgG4 subclass, which is less potent in immune activation and largely circulate with monovalent bispecificity because of a spontaneous Fab arm exchange but may still block the effects of its target [146]

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Also, it may be more relevant for extreme paracetamol toxicity in patients (3)

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Particular attention was also taken to use animal-handling techniques that reduce stress and promote animal welfare (Sensini et al., 2020)